Nigerian Institute of Medical Research – COVID-19 Fractional Dosing Trial
Verified[Biosecurity & Pandemic Preparedness] Open Philanthropy recommended a grant of $2,921,000 to the Nigerian Institute of Medical Research to support a safety and immunogenicity trial in adults in Nigeria of fractional doses of the AstraZeneca, Pfizer, and Johnson & Johnson COVID-19 vaccines. The trial has the potential to indicate that smaller doses of these vaccines promote immune responses that are "non-inferior" to those from standard doses. If non-inferiority can be established, this could allow many people to be vaccinated against COVID-19 sooner despite limited supplies, and potentially affect booster recommendations in Nigeria or elsewhere, reducing deaths and other harms from the pandemic. This falls within our work on scientific research, and specifically within our interest in science supporting biosecurity and pandemic preparedness.
Other Grants by Coefficient Giving
2625| Grant | Recipient | Amount | Date |
|---|---|---|---|
| Janaagraha — Air Quality Grants Assessment | $195K | Dec 2024 | |
| Futurewise — Housing Advocacy in Washington | $450K | Apr 2023 | |
| Exscientia — Agonists for Interferon Lambda | $2.3M | Sep 2023 | |
| Kurzgesagt — Short-form Video Content | $3M | Mar 2022 | |
| Kurzgesagt — Video Production (2023) | $1.7M | May 2023 | |
| Kurzgesagt — Video Creation and Translation | $2.6M | Dec 2021 | |
| Lightcone Infrastructure – General Support | Lighthaven (Event Venue) | $4.5M | Sep 2022 |
| Lightcone Infrastructure — General Support (2023) | Lighthaven (Event Venue) | $3M | Oct 2023 |
| Conjecture — Cybersecurity Bootcamp | Conjecture | $223K | Jun 2025 |
| Conjecture — AI Safety Technical Program | Conjecture | $224K | May 2023 |