University of Oxford — Monoclonal Antibody Development for Malaria

[Global Health R&D] Open Philanthropy recommended a gift of $300,000 to the University of Oxford to support work led by Professor Simon Draper on the clinical development of a blood-stage malaria RH5 monoclonal antibody (mAb). Due to its key role in invading a host’s red blood cells, the RH5 protein is a promising target for mAb therapy. These funds will provide support to Professor Draper's team to accelerate the manufacture of clinical grade GMP RH5 mAb and preparation for human clinical trials. This falls within our focus area of global health R&D.