Science and Global Health R&D Fund – Coefficient Giving
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This is a global health R&D funding page from Coefficient Giving, focused on neglected disease research including vaccines and drugs. It has minimal direct relevance to AI safety, though it mentions AI-assisted vaccine design (David Baker's Nobel Prize work), touching tangentially on AI capabilities in biomedical contexts.
Metadata
Summary
Coefficient Giving's Science and Global Health R&D Fund supports research into new tools to improve global health, focusing on neglected diseases like tuberculosis, malaria, and rheumatic heart disease. The fund covers basic research, preclinical/clinical studies, and implementation research. It has operated since 2016 and expanded its global health R&D work in 2023.
Key Points
- •Funds R&D for neglected diseases disproportionately affecting the world's poorest populations, where funding gaps are 10x or more relative to disease burden.
- •Supports transformative basic research, clinical trials for new treatments/vaccines/diagnostics, and implementation research.
- •Launched an RFP for generic drug repurposing to accelerate treatment options for high-burden neglected diseases.
- •Highlights AI-assisted vaccine design, including grantee David Baker's Nobel Prize-winning protein design work.
- •Partners include Good Ventures, Patchwork Collective, and private funders.
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Science and Global Health R&D
We support research and development into new tools to improve global health.
Contents
About the Fund
Research & Updates
Featured Grants
About the Fund
Team
Chris Smith
Program Director
Chris Somerville
Program Director
Heather Youngs
Program Director
Katharine Collins
Senior Program Officer
Ray Kennedy
Senior Program Officer
Aisling Leow
Associate Program Officer
Rafael Dib
Senior Program Associate
Partners
Good Ventures
Patchwork Collective
Private funders (x3)
Interested in learning more or joining the fund? Reach out to partnerwithus@coefficientgiving.org .
Health technologies like vaccines and drugs save millions of lives around the world. Yet many cures remain undiscovered. Government and private sector funders do not always prioritize research and development (R&D) that could help the most people live long and healthy lives.
Diseases like tuberculosis, malaria, and rheumatic heart disease that primarily affect the world’s poorest people receive much less R&D spending relative to their health burdens than diseases affecting the wealthy. High-risk, transformational science often goes unfunded, too.
We are particularly interested in supporting products or fields where progress has stalled, where additional resources could accelerate breakthrough discoveries and new tools for global health.
We have supported scientific research for human health since 2016, expanding our work in global health R&D in 2023. Our work includes:
Transformative basic research and tool development aimed at answering fundamental questions about biology and human health.
Preclinical and clinical studies to develop and test new treatments , vaccines , diagnostics , and other preventive technologies .
Implementation research , technical assistance , and market-shaping initiatives to help health systems make use of the best knowledge and tools available, and expand the availability of lifesaving technologies.
Request for Proposals
RFP on Generic Drug Repurposing
Coefficient Giving is launching a Request for Proposals to fund rigorous investigations of repurposed generic drugs for high-burden yet neglected diseases. We are seeking proposals to move promising candidates toward clinical evidence of efficacy — leveraging the speed, cost, and access advantages that repurposing offers to deliver new treatment options for patients who cannot wait for the next generation of drug discovery.
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Research & Updates
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A Quantitative Approach to Vaccine Funding
Some diseases that kill many people re
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