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JCI: AlphaFold developers share 2023 Lasker Award

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This short viewpoint is relevant as background context on AlphaFold's scientific impact and recognition; it illustrates transformative AI capabilities in science but has limited direct AI safety content.

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Importance: 25/100news articlenews

Summary

This JCI viewpoint article celebrates the 2023 Albert Lasker Basic Medical Research Award given to Demis Hassabis and John Jumper of DeepMind for developing AlphaFold, the AI system that solved the protein structure prediction problem. The piece contextualizes AlphaFold's transformative impact on biological sciences since its 2020 announcement, noting how widespread its adoption has become in research.

Key Points

  • Demis Hassabis and John Jumper received the 2023 Lasker Award for inventing AlphaFold, which predicts 3D protein structures from 1D amino acid sequences.
  • AlphaFold's impact is described as so pervasive that 'I alphafolded it' has become common scientific vernacular, analogous to 'I googled it'.
  • The announcement of AlphaFold's success in November 2020 marked a revolution in biological sciences, solving a decades-long grand challenge.
  • The article reflects on AI's capacity to solve fundamental scientific problems, relevant to discussions of AI capabilities and transformative potential.
  • Recognition by the Lasker Award signals broad scientific consensus that AlphaFold represents a landmark achievement in AI-driven science.

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AlphaFold developers Demis Hassabis and John Jumper share the 2023 Albert Lasker Basic Medical Research Award
 

 
 
 

 

 

 
 
 
 
 
 
 
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Open Access | 10.1172/JCI174915 
 

 
 
 
 
 
 
 
 
 
 
 
 

 
 

 
 

 AlphaFold developers Demis Hassabis and John Jumper share the 2023 Albert Lasker Basic Medical Research Award

 
 
 Tobin R. Sosnick
 

 
 Department of Biochemistry and Molecular Biology, Pritzker School of Molecular Engineering, Institute for Biophysical Dynamics, University of Chicago, Chicago, Illinois, USA.

 
 Address correspondence to: Tobin R. Sosnick, Department of Biochemistry and Molecular Biology, Pritzker School of Molecular Engineering, Institute for Biophysical Dynamics, University of Chicago, 929 E. 57th St., GCIS Room W101C, Chicago, Illinois, 60637 USA. Phone: 773.218.5950; Email: trsosnic@uchicago.edu .

 
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Published September 21, 2023
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Published in
 Volume 133, Issue 19 
on
October 2, 2023

 
J Clin Invest.
 
2023;133(19):e174915.
 https://doi.org/10.1172/JCI174915 .

© 2023 Sosnick
This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
 

 
Published September 21, 2023
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 The 2023 Albert Lasker Basic Medical Research Award has been given to Demis Hassabis and John Jumper of DeepMind for the invention of AlphaFold, the artificial intelligence (AI) system that solved the long-standing challenge of predicting the three-dimensional (3D) structure of proteins from the one-dimensional (1D) sequence of their amino acids.

 The expression “I alphafolded it” is now something I hear almost every day, whether in the lab, during a thesis defense, or at a scientific conference. 

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Resource ID: 2fee4e5ef75fbe8b | Stable ID: sid_Wmnyydi0pP