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Credibility Rating

4/5
High(4)

High quality. Established institution or organization with editorial oversight and accountability.

Rating inherited from publication venue: MacArthur Foundation

Tangentially relevant to AI safety as a major philanthropic funding mechanism; the Sentinel pandemic prevention award touches on catastrophic biological risk reduction, a concern overlapping with existential risk communities, but the program is not focused on AI safety.

Metadata

Importance: 18/100homepage

Summary

The MacArthur Foundation's 100&Change competition awards a single $100 million grant to fund a proposal promising real and measurable progress on a critical global problem. The most recent award went to the Broad Institute's Sentinel project for pandemic prevention through improved early detection and containment of infectious disease outbreaks. The competition is open to organizations worldwide and evaluates proposals on significance, effectiveness, feasibility, and durability.

Key Points

  • Single $100 million grant awarded to one proposal addressing a critical global problem with measurable impact
  • 2024/2025 cycle awarded to Sentinel (Broad Institute) for global pandemic early detection and containment
  • Competition is open to any organization worldwide, not limited to specific sectors or issue areas
  • Proposals evaluated on significance, effectiveness, feasibility, and durability criteria
  • Pandemic prevention and biosecurity are among funded priorities, relevant to catastrophic risk reduction

Cited by 1 page

PageTypeQuality
MacArthur FoundationOrganization65.0

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100&Change - MacArthur Foundation 
 
 
 
 
 
 

 
 

 
 
 
 
 
 
 
 

 
 
 

 
 
 
 
 
 
 
 

 
 
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 100&Change

 
 
 
 A competition for a $100 million grant to fund a single proposal that promises real and measurable progress in solving a critical problem of our time. 
 #100andChange 
 
 
 
 Overview 
 Strategy 
 Timeline 
 Award Recipients 
 FAQs 
 Perspectives 
 News 
 
 
 
 
 
 
 
 
 
 

 
 

 
 Meet the 2025 Finalists

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 Sentinel Awarded $100 Million to Prevent Pandemics

 The Broad Institute's Sentinel project will change how communities approach early detection and containment of infectious disease outbreaks globally.

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 100&Change Finalists Share Insights on Their Proposals

 Explore Their Perspectives 
 

 
 
 
 
 
 Stay Informed

 Sign up to receive announcements for the 100&Change competition. 
 
 
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 Competition Timeline

 
 


 
 
 
 
 
 $100 Million Award Recipient 

 
 
 Community Solutions

 Awarded 2021 
 Accelerating an end to homelessness in 75 U.S. communities in five years

 Learn More Read the Press Release 
 
 
 
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 Latest News & Related Content

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 Other Awards 

 MacArthur Fellows

 Celebrating and inspiring the creative potential of individuals through no-strings-attached fellowships.
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