Coefficient Giving - NTI GCBR Projects
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This is the homepage for Coefficient Giving's biosecurity fund, a major philanthropic funder in the GCB risk space; relevant to understanding funding landscape and institutional priorities in biosecurity as it intersects with AI safety.
Metadata
Summary
Coefficient Giving (formerly Open Philanthropy's biosecurity program) is a philanthropic fund supporting work to reduce global catastrophic biological risks, having made 140+ grants totaling $260+ million. The fund focuses on technological biosecurity threats, pandemic preparedness, and mitigating risks from advanced biotechnology and AI. Key initiatives include developing respiratory protection, advancing metagenomic sequencing, and supporting research and policy to prevent catastrophic biological events.
Key Points
- •Fund has made 140+ grants totaling over $260 million in biosecurity and pandemic preparedness work
- •Prioritizes risks from advanced biotechnology and AI that could exceed natural pandemic severity
- •Supports defensive technologies like metagenomic sequencing for early pathogen detection
- •Work began five years before COVID-19, reflecting long-term focus on catastrophic biological risk
- •Frames biological risks as potential extinction-level threats capable of derailing human civilization
Cited by 1 page
| Page | Type | Quality |
|---|---|---|
| NTI | bio (Nuclear Threat Initiative - Biological Program) | Organization | 60.0 |
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Biosecurity & Pandemic Preparedness | Coefficient Giving
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Biosecurity & Pandemic Preparedness
We support work to guard against catastrophic biological risks, especially ones from advanced technology.
140+
grants made
$260+
million given
Contents
About the Fund
Research & Updates
Featured Grants
About the Fund
Team
Andrew Snyder-Beattie
Managing Director
Conor McGurk
Chief of Staff
James Wagstaff
Senior Program Officer
Chris Bakerlee
Associate Program Officer
Christian Ruhl
Associate Program Officer
Aman Patel
Senior Program Associate
Damon Binder
Senior Research Analyst
Constantin Arnscheidt
Research Fellow
Neha Singh
Operations Lead
Partners
Good Ventures
Interested in providing funding within this space? Reach out to partnerwithus@coefficientgiving.org .
Disease outbreaks have been responsible for some of the deadliest events in human history. Over five years, COVID-19 caused tens of millions of excess deaths and shrank the global economy by tens of trillions of dollars. But that was far from a worst-case scenario: advances in biotechnology and AI could make future biological risks even more severe than natural diseases. These risks could be among the greatest threats to society — capable of derailing centuries of progress or even causing human extinction.
Since our work on biosecurity began — five years before COVID-19 — we’ve been supporting research, technology, and policy initiatives aimed at preventing these risks and mitigating their consequences, with a particular focus on technological risks. Access to the right tools and knowledge could save millions of lives in future catastrophic biological events.
Our grantees’ work includes:
Developing widespread affordable respiratory protection to protect healthcare staff and other essential workers in the event of a pandemic.
Advancing defensive technologies like metagenomic sequencing to detect pathogens and Far-UVC light to disinfect shared spaces.
Improving governance and security, through stronger international norms on biological weapons, dual-use research oversight, mirror bacteria , and DNA synthesis screening.
Research & Updates
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Request for Proposals
Request for Proposals: Biosecurity
We want to support work aimed at preventing engineered biological threats from emerging and improving our response to these threats should prevention fail. We’re eager to fund
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