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Rajpurkar et al. (2017)

paper

Authors

Pranav Rajpurkar·Jeremy Irvin·Kaylie Zhu·Brandon Yang·Hershel Mehta·Tony Duan·Daisy Ding·Aarti Bagul·Curtis Langlotz·Katie Shpanskaya·Matthew P. Lungren·Andrew Y. Ng

Credibility Rating

3/5
Good(3)

Good quality. Reputable source with community review or editorial standards, but less rigorous than peer-reviewed venues.

Rating inherited from publication venue: arXiv

CheXNet demonstrates AI medical imaging capabilities exceeding radiologist performance, illustrating both the potential for AI in healthcare and the importance of rigorous evaluation, robustness testing, and alignment between AI system capabilities and real-world deployment safety requirements.

Paper Details

Citations
3,175
325 influential
Year
2017
Methodology
peer-reviewed
Categories
Anais do XLI Simpósio Brasileiro de Telecomunicaçõ

Metadata

arxiv preprintprimary source

Abstract

We develop an algorithm that can detect pneumonia from chest X-rays at a level exceeding practicing radiologists. Our algorithm, CheXNet, is a 121-layer convolutional neural network trained on ChestX-ray14, currently the largest publicly available chest X-ray dataset, containing over 100,000 frontal-view X-ray images with 14 diseases. Four practicing academic radiologists annotate a test set, on which we compare the performance of CheXNet to that of radiologists. We find that CheXNet exceeds average radiologist performance on the F1 metric. We extend CheXNet to detect all 14 diseases in ChestX-ray14 and achieve state of the art results on all 14 diseases.

Summary

Rajpurkar et al. (2017) present CheXNet, a 121-layer convolutional neural network trained on ChestX-ray14, the largest publicly available chest X-ray dataset with over 100,000 images labeled for 14 diseases. The model achieves pneumonia detection performance exceeding that of practicing radiologists on the F1 metric. The authors extend CheXNet to detect all 14 diseases in the dataset and demonstrate state-of-the-art results across all disease categories, representing a significant advance in automated medical image analysis.

Cited by 1 page

PageTypeQuality
AI-Human Hybrid SystemsApproach91.0

Cached Content Preview

HTTP 200Fetched Apr 9, 202627 KB
[1711.05225] Chest 
 
 
 
 
 
 
 
 
 
 
 

 
 
 

 
 
 
 
 
 
 Chest

 
 
 Pranav Rajpurkar
 
    
 Jeremy Irvin
 
    
 Kaylie Zhu
 
    
 Brandon Yang
 
    
 Hershel Mehta
 
    
 Tony Duan
 
    
 Daisy Ding
 
    
 Aarti Bagul
 
    
 Robyn L. Ball
 
    
 Curtis Langlotz
 
    
 Katie Shpanskaya
 
    
 Matthew P. Lungren
 
    
 Andrew Y. Ng
 
 

 CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learning

 
 
 Pranav Rajpurkar
 
    
 Jeremy Irvin
 
    
 Kaylie Zhu
 
    
 Brandon Yang
 
    
 Hershel Mehta
 
    
 Tony Duan
 
    
 Daisy Ding
 
    
 Aarti Bagul
 
    
 Robyn L. Ball
 
    
 Curtis Langlotz
 
    
 Katie Shpanskaya
 
    
 Matthew P. Lungren
 
    
 Andrew Y. Ng
 
 

 
 Abstract

 We develop an algorithm that can detect pneumonia from chest X-rays at a level exceeding practicing radiologists. Our algorithm, CheXNet, is a 121-layer convolutional neural network trained on ChestX-ray14, currently the largest publicly available chest X-ray dataset, containing over 100,000 frontal-view X-ray images with 14 diseases. Four practicing academic radiologists annotate a test set, on which we compare the performance of CheXNet to that of radiologists. We find that CheXNet exceeds average radiologist performance on the F1 metric. We extend CheXNet to detect all 14 diseases in ChestX-ray14 and achieve state of the art results on all 14 diseases.

 
 healthcare, medical imaging, convolutional neural networks, xrays, pneumonia
 
 
 Figure 1 : 
CheXNet is a 121-layer convolutional neural network that takes a chest X-ray image as input, and outputs the probability of a pathology. On this example, CheXnet correctly detects pneumonia and also localizes areas in the image most indicative of the pathology.
 
 † † Project website at https://stanfordmlgroup.github.io/projects/chexnet 
 
 
 1 Introduction

 
 More than 1 million adults are hospitalized with pneumonia and around 50,000 die from the disease every year in the US alone (CDC, 2017 ) . Chest X-rays are currently the best available method for diagnosing pneumonia (WHO, 2001 ) , playing a crucial role in clinical care (Franquet, 2001 ) and epidemiological studies (Cherian et al., 2005 ) . However, detecting pneumonia in chest X-rays is a challenging task that relies on the availability of expert radiologists. In this work, we present a model that can automatically detect pneumonia from chest X-rays at a level exceeding practicing radiologists.

 
 
 Our model, ChexNet (shown in Figure 1 ), is a 121-layer convolutional neural network that inputs a chest X-ray image and outputs the probability of pneumonia along with a heatmap localizing the areas of the image most indicative of pneumonia. We train CheXNet on the recently released ChestX-ray14 dataset (Wang et al., 2017 ) , which contains 112,120 frontal-view chest X-ray images individually labeled with up to 14 different thoracic diseases, including pneumonia. We use dense connections (Huang et al., 2016 ) and bat

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