| Johns Hopkins Center for Health Security — Biosecurity, Global Health Security, and Global Catastrophic Risks (2019) | Johns Hopkins Center for Health Security | $20M | Sep 2019 | |
| Sherlock Biosciences — Research on Viral Diagnostics | Sherlock Biosciences | $18M | Jan 2019 | |
| RAND Corporation — Biosecurity Policy | RAND | $17M | May 2023 | |
| Johns Hopkins Center for Health Security — Biosecurity, Global Health Security, and Global Catastrophic Risks (2017) | Johns Hopkins Center for Health Security | $16M | Jan 2017 | |
| Californians Against Pandemics — California Pandemic Early Detection and Prevention Act Ballot Initiative | Californians Against Pandemics | $11M | Oct 2021 | |
| Johns Hopkins Center for Health Security — Biosecurity, Global Health Security, and Global Catastrophic Risks (2023) | Johns Hopkins Center for Health Security | $10M | Mar 2023 | |
| Nuclear Threat Initiative — Biosecurity Program Support (February 2020) | NTI | bio (Nuclear Threat Initiative - Biological Program) | $8M | Feb 2020 | |
| Nuclear Threat Initiative — Biosecurity Program Support (2023) | NTI | bio (Nuclear Threat Initiative - Biological Program) | $7.8M | Apr 2023 | |
| Blueprint Biosecurity — Regranting Support | Blueprint Biosecurity | $7.1M | May 2025 | |
| Council on Strategic Risks — Biosecurity Fellowships, Policy, and General Operations | Council on Strategic Risks | $6.5M | Nov 2024 | |
| Icosavax — COVID-19 Vaccine Development | Icosavax | $6.5M | Aug 2020 | |
| Blueprint Biosecurity — General Support (2025) | Blueprint Biosecurity | $6.4M | Aug 2025 | |
| Nuclear Threat Initiative — Biosecurity Program Support | NTI | bio (Nuclear Threat Initiative - Biological Program) | $6M | Oct 2017 | |
| Centre for Effective Altruism — Biosecurity Coworking Space | Centre for Effective Altruism | $5.3M | Aug 2022 | |
| Bipartisan Commission on Biodefense — General Support (2022) | Bipartisan Commission on Biodefense | $5.2M | Jul 2022 | |
| The Centre for Long-Term Resilience — General Support | The Centre For Long Term Resilience | $5.1M | Aug 2024 | |
| Alvea — DNA Vaccine Platform | Alvea | $5M | May 2022 | |
| Good Forever — Regranting for Biosecurity Projects | Good Forever Foundation | $4.9M | Feb 2022 | |
| Bipartisan Commission on Biodefense — General Support (2025) | Bipartisan Commission on Biodefense | $4.6M | Jan 2025 | |
| SecureBio — General Support | SecureBio | $4M | Nov 2024 | |
| Johns Hopkins Center for Health Security — Educational Degree Program | Johns Hopkins Center for Health Security | $3.9M | Sep 2022 | |
| Nuclear Threat Initiative — Global Health Security Index | NTI | bio (Nuclear Threat Initiative - Biological Program) | $3.6M | Jul 2018 | |
| KU Leuven — Influenza Antiviral Research | KU Leuven | $3.5M | Apr 2024 | |
| Georgetown Center for Global Health Science and Security — General Support (2017) | Georgetown Center for Global Health Science and Security | $3.5M | Mar 2017 | |
| SecureBio — Nucleic Acid Observatory | SecureBio | $3.4M | Feb 2025 | |
| Center for Security and Emerging Technology — Biosecurity Research Project | CSET (Center for Security and Emerging Technology) | $3.3M | Aug 2021 | |
| Blueprint Biosecurity — Policy Advocacy | Blueprint Biosecurity | $3.2M | May 2025 | |
| Columbia University — Far-UVC Sterilization Research | Columbia University | $3.2M | Jun 2022 | |
| Bipartisan Commission on Biodefense — General Support | Bipartisan Commission on Biodefense | $3M | Feb 2020 | |
| Nigerian Institute of Medical Research – COVID-19 Fractional Dosing Trial | Nigerian Institute Of Medical Research | $2.9M | Jan 2022 | |
| Council on Strategic Risks — Biosecurity Fellowships and Policy Work | Council on Strategic Risks | $2.9M | Sep 2022 | |
| Johns Hopkins Center for Health Security — Emerging Leaders in Biosecurity Initiative | Johns Hopkins Center for Health Security | $2.7M | Oct 2016 | |
| Massachusetts Institute of Technology Media Lab — Biosecurity Research (2022) | Massachusetts Institute of Technology | $2.6M | Dec 2022 | |
| Blue Ribbon Study Panel on Biodefense— General Support (2018) | Bipartisan Commission on Biodefense | $2.6M | Jan 2018 | |
| Harvard University — Antiviral Research (2022) | Harvard University | $2.5M | Jan 2022 | |
| Open Philanthropy Biosecurity Scholarships (2022) | Scholarship (Various) | $2.4M | Jan 2022 | |
| Georgetown Center for Global Health Science and Security — General Support (March 2020) | Georgetown Center for Global Health Science and Security | $2.4M | Mar 2020 | |
| Global Shield — Global Catastrophic Risks Advocacy | Global Shield | $2.3M | Feb 2025 | |
| Exscientia — Agonists for Interferon Lambda | | $2.3M | Sep 2023 | |
| Council on Strategic Risks — Biological Weapons Prevention (November 2020) | Council on Strategic Risks | $2M | Nov 2020 | |
| Binx — COVID-19 Testing Platform | Binx | $2M | Nov 2020 | |
| Gryphon Scientific — Empirical Biosafety Research | Gryphon Scientific | $2M | May 2020 | |
| Nuclear Threat Initiative — Projects to Reduce Global Catastrophic Biological Risks | NTI | bio (Nuclear Threat Initiative - Biological Program) | $1.9M | Nov 2018 | |
| Johns Hopkins Center for Health Security — Masters and PhD Program Support | Johns Hopkins Center for Health Security | $1.9M | Feb 2020 | |
| Evotec — Henipavirus Antivirals | Evotec | $1.8M | Mar 2023 | |
| Center for International Security and Cooperation — Megan Palmer’s Biosecurity Research (2019) | Stanford University | $1.6M | Jan 2019 | |
| SecureBio — Biosecurity Research | SecureBio | $1.4M | Nov 2022 | |
| Early-Career Funding for Global Catastrophic Biological Risks — Scholarship Support (2019-2020) | Early Career Funding For Global Catastrophic Biological Risks | $1.4M | Jul 2020 | |
| Bipartisan Commission on Biodefense — General Support (2021) | Bipartisan Commission on Biodefense | $1.4M | Dec 2021 | |
| Blue Ribbon Study Panel on Biodefense — General Support (2016) | Bipartisan Commission on Biodefense | $1.3M | Aug 2016 | |
| Alvea — Drug Development Acceleration (October 2022) | Alvea | $1.3M | Oct 2022 | |
| Nuclear Threat Initiative — Global Catastrophic Biological Risk Reduction (2021) | NTI | bio (Nuclear Threat Initiative - Biological Program) | $1.3M | Dec 2021 | |
| Georgetown Center for Global Health Science and Security — General Support (February 2020) | Georgetown Center for Global Health Science and Security | $1.2M | Feb 2020 | |
| Eradivir — Influenza Antiviral Drug | Eradivir | $1M | Jul 2023 | |
| Massachusetts Institute of Technology Media Lab — Kevin Esvelt’s Research (2021) | Massachusetts Institute of Technology | $1M | Mar 2021 | |
| iGEM — Synthetic Biology Safety and Security (2020) | International Genetically Engineered Machine Foundation | $940K | Apr 2020 | |
| World Health Organization — Responsible Life Sciences Research | World Health Organization | $900K | Jul 2023 | |
| Blueprint Biosecurity — General Support (2024) | Blueprint Biosecurity | $900K | Oct 2024 | |
| Massachusetts Institute of Technology Media Lab — DNA Synthesis Screening Methods | Massachusetts Institute of Technology | $890K | Oct 2020 | |
| Georgia Tech — Research on Lipid Nanoparticles (James Dahlman) | Georgia Institute of Technology | $882K | Apr 2021 | |
| CSIRO — Henipavirus Research | CSIRO | $779K | May 2023 | |
| University of Pretoria — Far-UVC Study | University Of Pretoria | $755K | Feb 2025 | |
| Center for International Security and Cooperation — Megan Palmer’s Biosecurity Research (2016) | Stanford University | $643K | Oct 2016 | |
| Carnegie Endowment for International Peace — Chinese and Indian Perspectives on Biotech Security Risks | Carnegie Endowment for International Peace | $613K | Dec 2017 | |
| Stanford University — Research on Lipid Nanoparticles (Jeffrey Glenn) | Stanford University | $610K | Apr 2021 | |
| 1Day Sooner — General Support (November 2020) | 1Day Sooner | $600K | Nov 2020 | |
| SecureBio — Pathogen Early Warning Project | SecureBio | $570K | Aug 2023 | |
| Early-Career Funding for Global Catastrophic Biological Risks — Scholarship Support (2018) | Early Career Funding For Global Catastrophic Biological Risks | $570K | May 2018 | |
| iGEM — Synthetic Biology Safety and Security (2016) | International Genetically Engineered Machine Foundation | $520K | May 2016 | |
| Blue Ribbon Study Panel on Biodefense — General Support (2017) | Bipartisan Commission on Biodefense | $500K | Jan 2017 | |
| Helena — Health Security Policy | Helena | $500K | Nov 2022 | |
| Nuclear Threat Initiative — Biosecurity Program Support (May 2020) | NTI | bio (Nuclear Threat Initiative - Biological Program) | $500K | May 2020 | |
| 1Day Sooner — General Support (May 2020) | 1Day Sooner | $500K | May 2020 | |
| Federation of American Scientists — Biosecurity and Pandemic Preparedness Fellowship | Federation of American Scientists | $480K | Aug 2021 | |
| Nuclear Threat Initiative — Planning Grant for Global Health Security Index | NTI | bio (Nuclear Threat Initiative - Biological Program) | $477K | Feb 2017 | |
| Genspace — DIYbio Labs Project | Genspace | $454K | May 2017 | |
| National Academies of Sciences, Engineering, and Medicine — International Meeting on Governance of Dual-Use Research | National Academies Of Sciences, Engineering, And Medicine | $453K | May 2017 | |
| Berkeley Existential Risk Initiative — Sculpting Evolution Collaboration | Berkeley Existential Risk Initiative | $452K | Nov 2021 | |
| Brown University — Pandemic Center | Brown University | $450K | Mar 2025 | |
| George Washington University — Innovation in National Security Fellowship | George Washington University | $450K | Aug 2021 | |
| Altruistic Technology Labs — Work on Biological Risk Prevention | Altruistic Technology Labs | $441K | May 2019 | |
| University of Utah — Henipavirus Antivirals (2024) | University of Utah | $428K | Jul 2024 | |
| Viroclinics Biosciences — Broad-Spectrum Antivirals | Viroclinics Biosciences | $422K | Nov 2018 | |
| iGEM — Synthetic Biology Safety and Security (2018) | International Genetically Engineered Machine Foundation | $420K | Nov 2018 | |
| Council on Strategic Risks — Biological Weapons Prevention (March 2020) | Council on Strategic Risks | $410K | Mar 2020 | |
| Rutgers University — Global Discussions of Life Sciences Governance | Rutgers University | $400K | Jun 2024 | |
| Convergent Research — Biosecurity Projects | Convergent Research | $400K | Oct 2023 | |
| University of Utah — Henipavirus Antivirals | University of Utah | $385K | Oct 2022 | |
| Johns Hopkins Center for Health Security — Health Security Scholars | Johns Hopkins Center for Health Security | $381K | May 2023 | |
| Open Philanthropy Biosecurity Scholarships (2023) | Scholarship (Various) | $352K | Nov 2022 | |
| Council on Strategic Risks — Biosecurity Fellowship | Council on Strategic Risks | $327K | May 2023 | |
| Sea-Long Global Respiratory Systems — COVID-19 Ventilation Helmet Production | Sea Long Global Respiratory Systems | $325K | Apr 2020 | |
| Harvard University — Biosecurity and Biosafety | Harvard University | $315K | Jun 2020 | |
| Smithsonian Institution — Outbreak Exhibit | Smithsonian Institution | $300K | Jul 2017 | |
| iGEM — Biological Weapons Convention Verification Project | IGem,International Genetically Engineered Machine Foundation | $300K | Nov 2021 | |
| Blue Ribbon Study Panel on Biodefense | Bipartisan Commission on Biodefense | $300K | Apr 2015 | |
| University of Maryland — Policy Fellowship (September 2023) | University of Maryland | $286K | Sep 2023 | |
| Massachusetts Institute of Technology Media Lab — General Support | Massachusetts Institute of Technology | $264K | Mar 2025 | |
| North Carolina State University — DIYbio Labs Project | North Carolina State University | $253K | May 2017 | |
| Science History Institute — Conference Fellowships | Science History Institute | $250K | Sep 2024 | |
| Charity Entrepreneurship — Health Security Organizations | Charity Entrepreneurship | $250K | Apr 2023 | |
| Convergent Research — Sequencing Roadmap | Convergent Research | $250K | Jun 2022 | |
| Center for Global Development — COVID-19 Local Response Guidelines | Center for Global Development | $250K | Mar 2020 | |
| University of Colorado — COVID-19 Personal Protective Equipment Experiments | University Of Colorado | $250K | Apr 2020 | |
| Center for Population-Level Bioethics — General Support | Center For Population Level Bioethics | $250K | May 2020 | |
| Center for a New American Security — Strategic Lessons from COVID-19 | Center for a New American Security | $250K | Mar 2021 | |
| Altruistic Technology Labs — Planning Grant | Altruistic Technology Labs | $250K | Dec 2020 | |
| Riboscience — COVID-19 Drug Research | Riboscience | $210K | Sep 2020 | |
| Effective Altruism Foundation — European Policy Research and Advocacy (April 2022) | Effective Altruism Foundation | $200K | Apr 2022 | |
| Stanford University — Pandemic Preparedness Center | Stanford University | $200K | Sep 2021 | |
| Good Forever Foundation — Pandemic Preparedness and COVID-19 Mitigation (2021) | Good Forever Foundation | $200K | Jan 2022 | |
| Stanford University — Biosecurity Workshop | Stanford University | $198K | Mar 2023 | |
| Harvard University — Center for Communicable Disease Dynamics | Harvard University | $190K | Jan 2023 | |
| National Animal Disease Center — Universal Influenza Antiviral Testing | National Animal Disease Center | $182K | May 2022 | |
| Federation of American Scientists — International Science Advisory Body for Biosecurity | Federation of American Scientists | $175K | Sep 2020 | |
| Johns Hopkins Center for Health Security — SynBioBeta 2018 Meeting | Johns Hopkins Center for Health Security | $170K | Jun 2018 | |
| Longview Philanthropy — Far-UVC Event (2023) | Longview Philanthropy | $165K | Feb 2023 | |
| Biosecure — Biological Weapons Convention Verification Workshop | Biosecure Ltd | $156K | Jul 2022 | |
| BioBricks Foundation — Biosecurity Activities at SB7.0 | BioBricks Foundation | $153K | Apr 2017 | |
| Council on Strategic Risks — Biosecurity Fellowship (2024) | Council on Strategic Risks | $141K | Jul 2024 | |
| Tyler Whitmer — Scoping Work for Biosecurity Legal Research | Tyler Whitmer | $125K | Dec 2022 | |
| Future of Humanity Institute — Biosecurity and Pandemic Preparedness | Future of Humanity Institute | $116K | Sep 2016 | |
| Berkeley Existential Risk Initiative — Support for Kevin Esvelt’s Research | Berkeley Existential Risk Initiative | $100K | Mar 2022 | |
| Icahn School of Medicine at Mount Sinai — Bat Cell Line Research | Icahn School Of Medicine At Mount Sinai | $100K | Dec 2021 | |
| Immune Observatory — Single-Dose COVID-19 Vaccine Modeling | Immune Observatory | $100K | Feb 2021 | |
| John Hopkins Center for Health Security — Health Security Scholars (2024) | Johns Hopkins Center for Health Security | $87K | Jun 2024 | |
| Centre for Effective Altruism — Research Assistant for Jonas Sandbrink | Centre for Effective Altruism | $77K | May 2022 | |
| University of Birmingham — Biological Threat Detection Research | University of Birmingham | $75K | May 2023 | |
| Longview Philanthropy — Far-UVC Event (2022) | Longview Philanthropy | $60K | Nov 2022 | |
| Mary Ann Liebert, Inc. — Open Source Biosafety Articles | Mary Ann Liebert Inc. | $50K | Feb 2024 | |
| Blueprint Biosecurity — General Support (2023) | Blueprint Biosecurity | $50K | Aug 2023 | |
| AcceleratingHT — COVID-19 Response | AcceleratingHT | $50K | Sep 2020 | |
| Global Health Security Network — Global Health Security Conference | Global Health Security Network | $50K | Nov 2020 | |
| Center for Global Development — Pandemic Policy Project Led by Jeremy Konyndyk | Center for Global Development | $50K | Feb 2018 | |
| Wilton Park — Biological Weapons Convention Retreat | Wilton Park | $48K | Sep 2022 | |
| Georgetown Center for Global Health Science and Security — General Support (2018) | Georgetown Center for Global Health Science and Security | $45K | Feb 2018 | |
| Wilton Park — Biological Weapons Convention Retreat (2024) | Wilton Park | $43K | Aug 2024 | |
| American Society for Microbiology — Biothreats Meeting | American Society For Microbiology | $43K | Dec 2017 | |
| University of Oxford — Genetic Engineering Attribution | University of Oxford | $40K | Jan 2023 | |
| The University of Sydney — 2019 Global Health Security Conference | University Of Sydney | $33K | Dec 2018 | |
| Synonym Bio — Food Production Research | Synonym Bio | $30K | Nov 2023 | |
| University of Oxford — D.Phil Support for Andrew Snyder-Beattie | University of Oxford | $26K | Oct 2018 | |
| Biosecure Ltd — Campaign Against Bioweapons Research | Biosecure Ltd | $25K | Dec 2018 | |
| Genspace — DIYbio and FBI Meeting | Genspace | $15K | Feb 2017 | |
| Brown Institute for Media Innovation — COVID-19 Rapid Micro-Grants | Brown Institute For Media Innovation | $15K | Apr 2020 | |
| InterAcademy Partnership — Side Event at the BWC Meeting of State Parties | InterAcademy Partnership | $15K | Nov 2017 | |
| Duke University — COVID-19 Antiviral Studies (Timothy Haystead) | Duke University | $14K | Mar 2021 | |
| Against COVID-19 — COVID-19 Database Support | Against COVID 19 | $10K | Mar 2020 | |
| Effective Altruism UK — Biosecurity Networking Event | Effective Altruism UK | $7.5K | Jun 2024 | |
| Tampere University — Work on Global Catastrophic Risks (2021) | Tampere University | $5.7K | Mar 2021 | |
| Oliver Crook — Travel Grant for Biological Attribution Event | Oliver Crook | $4.6K | Jan 2023 | |
| Ryan Teo — Publishing Fees for BWC Paper | Ryan Teo | $3.6K | Sep 2022 | |